Activin AB (ACVAB)

Wikipedia

Cloud-Clone

A158

PubMed

11995920

The effect of activins AB and B on DNA synthesis stimulated by epidermal growth factor (EGF) was studied in primary cultured rat hepatocytes and compared with the effect of activin A, a suppressor of DNA synthesis. Activin AB inhibited DNA synthesis as assessed by [3H]thymidine incorporation. The inhibition by activin AB was detected at 6 ng/ml, and the 12.5 ng/ml concentration produced almost maximal inhibition, approximately 40%, almost the same as that produced by activin A. Inhibition by activin A was detected at 3 ng/ml, and the 6 ng/ml concentration produced almost maximal inhibition. The increase in labeling index by EGF was also reduced to about 20% by 25 ng/ml activin A and activin AB, but not by activin B. Activin AB may act in the same manner as activin A does in terms EGF"s inhibitory effect on DNA synthesis, although the effective concentration is higher than that of activin A.

Организм

Артикул

Наименование

В наличии

ELISA Kit for Activin AB (ACVAB)

Организм:

Человек

Артикул:

SEA158Hu

ELISA Kit for Activin AB (ACVAB)

В наличии: