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Mothers Against Decapentaplegic Homolog 8 (Smad8)

UniProt

Q865B1

Cloud-Clone

S700

PubMed

19211612

Smad8, which lacks the C-terminal SSXS phosphorylation motif present in other Smads, and which appears to function in the BMP signaling pathway. Smad8 can block BMP-4-mediated induction of ventral mesoderm-specific gene expression in ectodermal explants. Smad8 may interact with additional signaling pathways. Indeed, overexpression of Smad8 blocks expression of Xbra in whole animals, and partially blocks activin signaling in animal caps. In addition, Smad8 inhibits involution of mesodermal cells during gastrulation, a phenotype that is not observed following blockade of activin or BMPs in Xenopus. Smad8 participates in a negative feedback loop in which BMP signaling induces the expression of Smad8, which then functions to negatively modulate the amplitude or duration of signaling downstream of BMPs and, possibly, downstream of other transforming growth factor-beta (TGF-beta) family ligands.

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Sandwich ELISA for Mothers Against Decapentaplegic Homolog 8 (Smad8)

Организм:

Лошадь

Артикул:

SES700Eq

Sandwich ELISA for Mothers Against Decapentaplegic Homolog 8 (Smad8)

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Sandwich ELISA for Mothers Against Decapentaplegic Homolog 8 (Smad8)

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SES700Ga

Sandwich ELISA for Mothers Against Decapentaplegic Homolog 8 (Smad8)

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Sandwich CLIA for Mothers Against Decapentaplegic Homolog 8 (Smad8)

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SCS700Eq

Sandwich CLIA for Mothers Against Decapentaplegic Homolog 8 (Smad8)

В наличии:

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Sandwich CLIA for Mothers Against Decapentaplegic Homolog 8 (Smad8)

Организм:

Курица

Артикул:

SCS700Ga

Sandwich CLIA for Mothers Against Decapentaplegic Homolog 8 (Smad8)

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Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 8 (Smad8)

Применение:

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PAS700Eq01

Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 8 (Smad8)

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Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 8 (Smad8)

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MAS700Eq21

Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 8 (Smad8)

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Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 8 (Smad8)

Применение:

Организм:

Курица

Артикул:

PAS700Ga01

Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 8 (Smad8)

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Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 8 (Smad8)

Применение:

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MAS700Ga21

Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 8 (Smad8)

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Recombinant protein Mothers Against Decapentaplegic Homolog 8 (Smad8)

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RPS700Eq01

Recombinant protein Mothers Against Decapentaplegic Homolog 8 (Smad8)

В наличии:

Уточнить

Recombinant protein Mothers Against Decapentaplegic Homolog 8 (Smad8)

Организм:

Курица

Артикул:

RPS700Ga01

Recombinant protein Mothers Against Decapentaplegic Homolog 8 (Smad8)

В наличии:

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