Granulocyte Specific Anti-Nuclear Antibody (GSANA)

Cloud-Clone

B619

PubMed

Antinuclear antibodies (ANA) generally do not show organ specificity and are detectable on a wide range of tissue substrates by the indirect immunofluorescent method. A notable exception is granulocyte-specific (GS) antibody, which reacts with nuclei of mature granulocytes (and monocytes) but not with nuclei of lymphocytes or cells of other tissues.GS-ANA occur uncommonly in health, and their highest incidence has been found in Felty"s syndrome, rheumatoid arthritis, and systemic lupus erythematosus. The titres of IgD granulocyte-specific antinuclear antibodies varied independently of the titres of IgD and complement-fixing granulocyte-specific antinuclear antibodies, but showed some covariation with granulocyte-specific antinuclear antibodies of the IgA and IgM classes most probably reflecting a broad polyclonal antibody response to phagocyte nuclear antigens in the serologically highly active neutropenic cases.

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Sandwich ELISA for Granulocyte Specific Anti-Nuclear Antibody (GSANA)

Организм:

Человек

Артикул:

SEB619Hu

Sandwich ELISA for Granulocyte Specific Anti-Nuclear Antibody (GSANA)

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