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Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

MGI

1351899

UniProt

Q9JJL3

Cloud-Clone

S904

RGD

69300

PubMed

21538436

Slco1b2 mice were fertile, developed normally, and exhibited no overt phenotypic abnormalities. Expression of Oatp1a4 and Oatp2b1 but not Oatp1a1 was greater in female Slco1b2 mice, but expression of other non-OATP transporters did not significantly differ between wild-type and Slco1b2 male mice. Total bilirubin level was elevated by 2-fold in the Slco1b2 mice despite the fact that liver enzymes ALT and AST were normal. Pharmacological characterization was carried out using two prototypical substrates of human OATP1B1 and -1B3, rifampin and pravastatin. This is the first report of altered drug disposition profile in the Slco1b2 knockout mice and suggests the utility of this model for understanding the in vivo role of hepatic OATP transporters in drug disposition.

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Sandwich ELISA for Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Артикул:

SES904Mu

Sandwich ELISA for Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Sandwich ELISA for Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Крыса

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SES904Ra

Sandwich ELISA for Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Sandwich CLIA for Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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SCS904Mu

Sandwich CLIA for Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Sandwich CLIA for Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Крыса

Артикул:

SCS904Ra

Sandwich CLIA for Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Polyclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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PAS904Mu01

Polyclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Monoclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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MAS904Mu21

Monoclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Polyclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

Применение:

Организм:

Крыса

Артикул:

PAS904Ra01

Polyclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

В наличии:

Уточнить

Monoclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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MAS904Ra21

Monoclonal Antibody to Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Recombinant Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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RPS904Mu01

Recombinant Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Recombinant protein Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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Крыса

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RPS904Ra01

Recombinant protein Solute Carrier Organic Anion Transporter Family, Member 1B2 (SLCO1B2)

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