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UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

MGI

3576049

UniProt

Q545X2

Cloud-Clone

S499

PubMed

9295054

In cultured primary hepatocytes UDP-glucuronosyltransferase form 1A2 (UGT1A2) mRNA level is 80 times higher than that found in rat liver.By contrast, NFI-C1 was present in rat liver but disappeared immediately upon cultivation of hepatocytes. Only trace amounts of NFI-B and NFI-X were detectable in rat liver and cultured hepatocytes. NFI-A1 elevated expression of the reporter gene that is under the control of CEREM, while NFI-C1 had an inhibitory effect. Co-expression of a constant amount of NFI-A1 with an increasing amount of NFI-C1 led to a concentration-dependent decrease in the expression of the CEREM-controlled reporter gene mediated by NFI-A1. Activation of UGT1A2 expression by NFI-A1 is suppressed by the coexistence of NFI-C1 in the liver, and culture-associated expression of UGT1A2 is triggered by the rapid disappearance of NFI-C1 in cultured hepatocytes.

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Sandwich ELISA for UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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SES499Mu

Sandwich ELISA for UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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Sandwich CLIA for UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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SCS499Mu

Sandwich CLIA for UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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Polyclonal Antibody to UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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PAS499Mu01

Polyclonal Antibody to UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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Monoclonal Antibody to UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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MAS499Mu21

Monoclonal Antibody to UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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Recombinant protein UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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RPS499Mu01

Recombinant protein UDP Glucuronosyltransferase 1 Family, Polypeptide A2 (UGT1A2)

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