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UV Stimulated Scaffold Protein A (UVSSA)

HUGO

29304

MGI

1918351

UniProt

Q2YD98

Cloud-Clone

V249

RGD

1306371

UV-sensitive syndrome (UVSS) is a genodermatosis characterized by cutaneous photosensitivity without skin carcinoma. Despite mild clinical features, cells from individuals with UVSS, like Cockayne syndrome cells, are very UV sensitive and are deficient in transcription-coupled nucleotide-excision repair (TC-NER), which removes DNA damage in actively transcribed genes. Three of the seven known UVSS cases carry mutations in the Cockayne syndrome genes ERCC8 or ERCC6. The remaining four individuals with UVSS, one of whom is described for the first time here, formed a separate UVSS-A complementation group; however, the responsible gene was unknown. The UVSSA protein interacts with TC-NER machinery and stabilizes the ERCC6 complex; it also facilitates ubiquitination of RNA polymerase IIo stalled at DNA damage sites.

Организм

Артикул

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В наличии

Sandwich ELISA for UV Stimulated Scaffold Protein A (UVSSA)

Организм:

Человек

Артикул:

SEV249Hu

Sandwich ELISA for UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Sandwich ELISA for UV Stimulated Scaffold Protein A (UVSSA)

Организм:

Мышь

Артикул:

SEV249Mu

Sandwich ELISA for UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Sandwich ELISA for UV Stimulated Scaffold Protein A (UVSSA)

Организм:

Крыса

Артикул:

SEV249Ra

Sandwich ELISA for UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Организм

Артикул

Наименование

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Sandwich CLIA for UV Stimulated Scaffold Protein A (UVSSA)

Организм:

Человек

Артикул:

SCV249Hu

Sandwich CLIA for UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Sandwich CLIA for UV Stimulated Scaffold Protein A (UVSSA)

Организм:

Мышь

Артикул:

SCV249Mu

Sandwich CLIA for UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Sandwich CLIA for UV Stimulated Scaffold Protein A (UVSSA)

Организм:

Крыса

Артикул:

SCV249Ra

Sandwich CLIA for UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Организм

Артикул

Наименование

В наличии

Polyclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

Применение:

Организм:

Человек

Артикул:

PAV249Hu01

Polyclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Monoclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

Применение:

Артикул:

MAV249Hu21

Monoclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Polyclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

Применение:

Организм:

Мышь

Артикул:

PAV249Mu01

Polyclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Monoclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

Применение:

Артикул:

MAV249Mu21

Monoclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Polyclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

Применение:

Организм:

Крыса

Артикул:

PAV249Ra01

Polyclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Monoclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

Применение:

Артикул:

MAV249Ra21

Monoclonal Antibody to UV Stimulated Scaffold Protein A (UVSSA)

В наличии:

Уточнить

Организм

Артикул

Наименование

В наличии